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pdxA:Quickview
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| Quickview | Gene | Gene Product(s) | Expression | Evolution | On One Page |
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| Standard Name |
pdxA |
|---|---|
| Gene Synonym(s) |
ECK0053, b0052, JW0051[1] |
| Product Desc. |
4-hydroxy-L-threonine phosphate dehydrogenase, NAD-dependent[2][3] 4-hydroxythreonine-4-phosphate dehydrogenase; fourth step in pyridoxal 5-phosphate biosynthesis; isoniazid resistance; requires divalent cations and NAD(P)+[4] |
| Product Synonyms(s) |
4-hydroxy-L-threonine phosphate dehydrogenase, NAD-dependent[1], B0052[2][1], PdxA[2][1] |
| Function from GO | |
| Knock-Out Phenotype | |
| Regulation/Expression |
transcription unit(s): imp-surA-pdxA[2], pdxA-rsmA[2], pdxA-ksgA, pdxA-rsmA-apaGH[2], pdxA-ksgA-apaG-apaH, surA-pdxA-rsmA-apaGH[2], surA-pdxA-ksgA-apaGH |
| Regulation/Activity | |
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Notes
Converts 4-hydroxy-L-threonine phosphate (HTP) to 3-amino-2-oxopropyl phosphate.[4]
References
- ↑ 1.0 1.1 1.2 1.3 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
- ↑ 2.0 2.1 2.2 2.3 2.4 2.5 2.6 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
- ↑ EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
- ↑ 4.0 4.1 EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.
