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polA:Quickview

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Standard Name

polA

Gene Synonym(s)

ECK3855, b3863, JW3835, resA[1], resA

Product Desc.

DNA polymerase I, 3' --> 5' polymerase, 5' --> 3' and 3' --> 5' exonuclease[2][3]

DNA polymerase I; required for plasmid replication; synthetic lethal with ygdG[4]

Product Synonyms(s)

fused DNA polymerase I 5'->3' exonuclease[1], 3'->5' polymerase[1], 3'->5' exonuclease[1], B3863[2][1], ResA[2][1], PolA[2][1] , ECK3855, JW3835, resA, b3863

Function from GO

Molecular Function

Knock-Out Phenotype
Regulation/Expression

transcription unit(s): polA[2]

Regulation/Activity
Quick Links

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Notes

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Residues 324-928 constitute the Klenow fragment.[4]



References

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  1. 1.0 1.1 1.2 1.3 1.4 1.5 1.6 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
  2. 2.0 2.1 2.2 2.3 2.4 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  3. EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  4. 4.0 4.1 EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.