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pth:Gene Product(s)

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Nomenclature Function Interactions Localization Sequence Domains Structure Resources Accessions Links References Suggestions

Nomenclature

See Help:Product_nomenclature for help entering or editing information in this section of EcoliWiki.

Standard name

Pth

Synonyms

peptidyl-tRNA hydrolase[1], B1204[2][1], Rap[2][1], Pth[2][1] , asuA?, ECK1192, JW1195, rap, b1204

Product description

peptidyl-tRNA hydrolase[2][3]

Peptidyl-tRNA hydrolase; required for phage lambda growth[4]

EC number (for enzymes)

Notes

Function

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Gene Ontology
See Help:Gene_ontology for help entering or editing GO terms and GO annotations in EcoliWiki.

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0004045

aminoacyl-tRNA hydrolase activity

GOA:hamap
GO_REF:0000020

IEA: Inferred from Electronic Annotation

HAMAP:MF_00083

F

Seeded from EcoCyc (v14.0)

complete

GO:0004045

aminoacyl-tRNA hydrolase activity

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR001328

F

Seeded from EcoCyc (v14.0)

complete

GO:0004045

aminoacyl-tRNA hydrolase activity

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR018171

F

Seeded from EcoCyc (v14.0)

complete

GO:0004045

aminoacyl-tRNA hydrolase activity

GOA:spec
GO_REF:0000003

IEA: Inferred from Electronic Annotation

EC:3.1.1.29

F

Seeded from EcoCyc (v14.0)

complete

GO:0005737

cytoplasm

GOA:hamap
GO_REF:0000020

IEA: Inferred from Electronic Annotation

HAMAP:MF_00083

C

Seeded from EcoCyc (v14.0)

complete

GO:0005737

cytoplasm

GOA:spkw
SP_KW:GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0963

C

Seeded from EcoCyc (v14.0)

complete

GO:0005737

cytoplasm

GO_REF:0000023

IEA: Inferred from Electronic Annotation

SP_SL:SL-0086

C

Seeded from EcoCyc (v14.0)

complete

GO:0006412

translation

GOA:hamap
GO_REF:0000020

IEA: Inferred from Electronic Annotation

HAMAP:MF_00083

P

Seeded from EcoCyc (v14.0)

complete

GO:0006412

translation

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR001328

P

Seeded from EcoCyc (v14.0)

complete

GO:0006412

translation

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR018171

P

Seeded from EcoCyc (v14.0)

complete

GO:0016787

hydrolase activity

GOA:spkw
SP_KW:GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0378

F

Seeded from EcoCyc (v14.0)

complete

Interactions See Help:Product_interactions for help entering or editing information about gene product interactions in this section of EcoliWiki.

Partner Type Partner Notes References Evidence

Protein

rpsB

PMID:15690043[5]

Experiment(s):EBI-878620, EBI-881343

Protein

tufA

PMID:15690043[5]

Experiment(s):EBI-878620

Protein

clpS

PMID:15690043[5]

Experiment(s):EBI-878620

Protein

prs

PMID:16606699[6]

Experiment(s):EBI-1139174

Protein

ccmB

PMID:15690043[5]

Experiment(s):EBI-881343

Protein

ispH

PMID:15690043[5]

Experiment(s):EBI-881343

Protein

groL

PMID:15690043[5]

Experiment(s):EBI-881343

Protein

rplD

PMID:15690043[5]

Experiment(s):EBI-881343

Protein

rplK

PMID:15690043[5]

Experiment(s):EBI-881343

Protein

rplL

PMID:15690043[5]

Experiment(s):EBI-881343

Protein

rplM

PMID:15690043[5]

Experiment(s):EBI-881343

Protein

rplV

PMID:15690043[5]

Experiment(s):EBI-881343

Protein

rpmB

PMID:15690043[5]

Experiment(s):EBI-881343

Protein

rpmG

PMID:15690043[5]

Experiment(s):EBI-881343

Protein

rpsJ

PMID:15690043[5]

Experiment(s):EBI-881343

Protein

groL

PMID:19402753[7]

LCMS(ID Probability):99.6

Protein

ispH

PMID:19402753[7]

LCMS(ID Probability):99.0

Notes

Localization

See Help:Product_localization for how to add or edit information in this section of EcoliWiki.

Compartment Description Evidence Reference/Source Notes

Notes

Structure and Physical Properties

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Physical Properties See Help:Product_physical_properties for help entering or editing information about the physical properties of this gene product.

Name
Sequence

at EcoCyc

MTIKLIVGLA NPGAEYAATR HNAGAWFVDL LAERLRAPLR EEAKFFGYTS RVTLGGEDVR
LLVPTTFMNL SGKAVAAMAS FFRINPDEIL VAHDELDLPP GVAKFKLGGG HGGHNGLKDI
ISKLGNNPNF HRLRIGIGHP GDKNKVVGFV LGKPPVSEQK LIDEAIDEAA RCTEMWFTDG
LTKATNRLHA FKAQ
Length

194

Mol. Wt

21.082 kDa

pI

9.3 (calculated)

Extinction coefficient

13,980 - 14,105 (calc based on 2 Y, 2 W, and 1 C residues)


Domains/Motifs/Modification Sites

See Help:Product_domains_motifs for help entering or editing information in this section of EcoliWiki.

Type Residues Description Notes References

Domain

5..189

PF01195 Peptidyl-tRNA hydrolase

PMID:19920124[8]


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Structure
See Help:Product_structure for help entering or editing information in this section of EcoliWiki.

Structures

No results found for a best structure.

Models

View models at:

Structure figures

Notes

Gene Product Resources

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See Help:Product_resources for help with entering or editing information in this section of EcoliWiki.

Resource type Source Notes/Reference

Notes

Accessions in Other Databases

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See Help:Gene_accessions for help with entering information into the Gene Accessions table.

Database Accession Notes

NCBI (Protein) (EcoliWiki Page)

GI:16129167

Escherichia coli str. K-12 substr. MG1655

NCBI (Protein) (EcoliWiki Page)

GeneID:945765

Escherichia coli str. K-12 substr. MG1655

ASAP

ASAP:ABE-0004043

Escherichia coli str. K-12 substr. MG1655

UniProt (EcoliWiki Page)

UniProtKB/Swiss-Prot:P0A7D1

Escherichia coli str. K-12 substr. MG1655

EcoCyc

EcoCyc:EG10785

Escherichia coli str. K-12 substr. MG1655

EcoGene

EcoGene:EG10785

Escherichia coli str. K-12 substr. MG1655

NCBI (Gene) (EcoliWiki Page)

GeneID:945765

Escherichia coli str. K-12 substr. MG1655

RegulonDB

RegulonDB:ECK120000776

Escherichia coli str. K-12 substr. MG1655

EchoBASE

EchoBASE:EB0778

Escherichia coli str. K-12 substr. MG1655

Notes

Links

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References

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See Help:References for how to manage references in EcoliWiki.

  1. 1.0 1.1 1.2 1.3 1.4 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
  2. 2.0 2.1 2.2 2.3 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  3. EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  4. EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.
  5. 5.00 5.01 5.02 5.03 5.04 5.05 5.06 5.07 5.08 5.09 5.10 5.11 5.12 5.13 Butland, G et al. (2005) Interaction network containing conserved and essential protein complexes in Escherichia coli. Nature 433 531-7 PubMed EcoliWiki page
  6. Arifuzzaman, M et al. (2006) Large-scale identification of protein-protein interaction of Escherichia coli K-12. Genome Res. 16 686-91 PubMed EcoliWiki page
  7. 7.0 7.1 Hu, P et al. (2009) Global functional atlas of Escherichia coli encompassing previously uncharacterized proteins. PLoS Biol. 7 e96 PubMed EcoliWiki page
  8. Finn, RD et al. (2010) The Pfam protein families database. Nucleic Acids Res. 38 D211-22 PubMed EcoliWiki page

Categories

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