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References Suggestions

Standard Name


Gene Synonym(s)

yggV, ECK2949, b2954, JW2921[1][2], JW2921

Product Desc.


dITP/XTP pyrophosphatase, synthetic lethal with recA; mutant is hyper-recombinogenic[4]

Product Synonyms(s)

dITP/XTP pyrophosphatase[1], B2954[2][1], YggV[2][1], RdgB[2][1] , ECK2949, JW2921, yggV, b2954

Function from GO

Molecular Function

Biological Process

Knock-Out Phenotype

transcription unit(s): yggS[2]

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2'-deoxy-N-6-hydroxylaminopurine triphosphate (dHAPTP) is a preferred substrate (Burgis, 2006). Mutations in nfi suppress the synthetic lethality.[4]


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  1. 1.0 1.1 1.2 1.3 1.4 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
  2. 2.0 2.1 2.2 2.3 2.4 2.5 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  3. EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  4. 4.0 4.1 EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.