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rluC:Gene Product(s)
From EcoliWiki
| Quickview | Gene | Gene Product(s) | Expression | Evolution | On One Page |
| Nomenclature | Function | Interactions | Localization | Sequence | Domains | Structure | Resources | Accessions | Links | References | Suggestions |
Nomenclature
| Standard name |
RluC |
|---|---|
| Synonyms |
23S rRNA pseudouridylate synthase[1], B1086[2][1], YceC[2][1], RluC[2][1] |
| Product description | |
| EC number (for enzymes) | |
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See Help:Product_nomenclature for help entering or editing information in this section of EcoliWiki.
Notes
Function
Gene Ontology
See Help:Gene_ontology for help entering or editing GO terms and GO annotations in EcoliWiki.
| Qualifier | GO ID | GO term name | Reference(s) | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0009982 |
pseudouridine synthase activity |
IDA: Inferred from Direct Assay |
F |
Seeded from EcoCyc 12.5 [5] |
complete | |||
| GO:0031118 |
rRNA pseudouridine synthesis |
IMP: Inferred from Mutant Phenotype |
P |
Seeded from EcoCyc 12.5 [5] |
complete | |||
| GO:0009982 |
pseudouridine synthase activity |
IEA: Inferred from Electronic Annotation |
F |
Seeded from EcoCyc 12.5 [5] |
complete | |||
| GO:0003723 |
RNA binding |
GO_REF:0000002 |
IEA: Inferred from Electronic Annotation |
InterPro:IPR002942 |
F |
Seeded from EcoCyc 12.5 [5] |
complete | |
| GO:0005737 |
cytoplasm |
C |
Seeded from EcoCyc 11.1[3]. |
required fields missing | ||||
| GO:0009451 |
RNA modification |
IMP: Inferred from Mutant Phenotype |
P |
Seeded from EcoCyc 10.6[2]. |
complete | |||
| GO:0016072 |
rRNA metabolic process |
IMP: Inferred from Mutant Phenotype |
P |
Seeded from EcoCyc 10.6[2]. |
complete | |||
| GO:0031118 |
rRNA pseudouridine synthesis |
IDA: Inferred from Direct Assay |
P |
Seeded from EcoCyc 12.5 [5] |
complete | |||
| GO:0000455 |
enzyme-directed rRNA pseudouridine synthesis |
IDA: Inferred from Direct Assay |
P |
complete | ||||
| GO:0003723 |
RNA binding |
F |
Seeded from EcoCyc 12.5 [5] |
required field missing | ||||
| GO:0031118 |
rRNA pseudouridine synthesis |
IDA: Inferred from Direct Assay |
P |
Seeded from EcoCyc 12.5 [5] |
complete | |||
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Interactions
| Partner Type | Partner | Notes | References |
|---|---|---|---|
| edit table |
See Help:Product_interactions for help entering or editing information about gene product interactions in this section of EcoliWiki.
Notes
Localization
| Compartment | Description | Evidence | Notes |
|---|---|---|---|
|
cytoplasm |
From EcoCyc[3] | ||
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See Help:Product_localization for how to add or edit information in this section of EcoliWiki.
Notes
Structure and Physical Properties
Physical Properties
| Sequence |
MKTETPSVKI VAITADEAGQ RIDNFLRTQL KGVPKSMIYR ILRKGEVRVN KKRIKPEYKL EAGDEVRIPP VRVAEREEEA VSPHLQKVAA LADVILYEDD HILVLNKPSG TAVHGGSGLS FGVIEGLRAL RPEARFLELV HRLDRDTSGV LLVAKKRSAL RSLHEQLREK GMQKDYLALV RGQWQSHVKS VQAPLLKNIL QSGERIVRVS QEGKPSETRF KVEERYAFAT LVRCSPVTGR THQIRVHTQY AGHPIAFDDR YGDREFDRQL TEAGTGLNRL FLHAAALKFT HPGTGEVMRI EAPMDEGLKR CLQKLRNAR |
|---|---|
| Mol. Wt |
36.03 kDa (calc) [2] |
| pI | |
| Extinction coefficient |
15930 - 16180 (calc based on 7 Y, 1 W, and 2 C residues) |
| edit table |
See Help:Product_physical_properties for help entering or editing information about the physical properties of this gene product.
Domains/Motifs/Modification Sites
| Type | Residues | Description | Notes |
|---|---|---|---|
|
Domain |
20 - 83 |
S4 RNA-binding | |
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Structure
| Structures |
|
|---|---|
| Models |
View models at: |
| edit table |
See Help:Product_structure for help entering or editing information in this section of EcoliWiki.
Notes
Gene Product Resources
| Resource type | Source | Notes/Reference |
|---|---|---|
| edit table |
See Help:Product_resources for help with entering or editing information in this section of EcoliWiki.
Notes
Accessions in Other Databases
| Database | Accession | Notes |
|---|---|---|
|
| ||
| edit table |
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Notes
Links
| Name | URL | Comments |
|---|---|---|
| edit table |
See Help:Links_table for how to enter or edit information in this section of EcoliWiki.
References
See Help:References for how to manage references in EcoliWiki.
- ↑ 1.0 1.1 1.2 1.3 1.4 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
- ↑ 2.0 2.1 2.2 2.3 2.4 2.5 2.6 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
- ↑ 3.0 3.1 3.2 EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
- ↑ 4.0 4.1 4.2 Huang L et al. (1998) Identification of two Escherichia coli pseudouridine synthases that show multisite specificity for 23S RNA. Biochemistry 37: 15951-7 PubMed EcoliWiki page
- ↑ 5.0 5.1 5.2 5.3 5.4 5.5 5.6 EcoCyc (release 12.5; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
- ↑ 6.0 6.1 6.2 6.3 Conrad J et al. (1998) The rluC gene of Escherichia coli codes for a pseudouridine synthase that is solely responsible for synthesis of pseudouridine at positions 955, 2504, and 2580 in 23 S ribosomal RNA. J Biol Chem 273: 18562-6 PubMed EcoliWiki page
Categories
Categories: GO:0009982 ! pseudouridine synthase activity | GO:0031118 ! rRNA pseudouridine synthesis | GO:0003723 ! RNA binding | GO:0005737 ! cytoplasm | GO:0009451 ! RNA modification | GO:0016072 ! rRNA metabolic process | GO:0000455 ! enzyme-directed rRNA pseudouridine synthesis | Proteins | Location:cytoplasm | Products with structures in PDB
