rplL:Gene Product(s) - EcoliWiki
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rplL:Gene Product(s)

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Nomenclature Function Interactions Localization Sequence Domains Structure Resources Accessions Links References Suggestions

Nomenclature

Standard name

RplL

Synonyms

50S ribosomal subunit protein L7/L12[1], B3986[2][1]

Product description

50S ribosomal subunit protein L7/L12[2]; 50S ribosomal subunit protein L7[3]; 50S ribosomal subunit protein L12[3];

Component of ; 50S ribosomal subunit protein L7/L12 dimer[3]; 50S ribosomal protein complex L8[3]; 50S ribosomal subunit[3]; ribosome[2][3]

EC number (for enzymes)
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Notes

Function

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Gene Ontology
See Help:Gene_ontology for help entering or editing GO terms and GO annotations in EcoliWiki.

QualifierGO IDGO term nameReference(s)Evidence Codewith/fromAspectNotesStatus
GO:0030529

ribonucleoprotein complex

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0687

C

Seeded from EcoCyc 12.5 [4]

complete

GO:0006412

translation

GO_REF:0000002
GO_REF:0000002
GO_REF:0000020

IEA: Inferred from Electronic Annotation

InterPro:IPR008932
InterPro:IPR013823
HAMAP:MF_00368

P

Seeded from EcoCyc 12.5 [4]

complete

GO:0005840

ribosome

GO_REF:0000002
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR008932
InterPro:IPR013823

C

Seeded from EcoCyc 12.5 [4]

complete

GO:0003735

structural constituent of ribosome

GO_REF:0000002
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR008932
InterPro:IPR013823

F

Seeded from EcoCyc 12.5 [4]

complete

GO:0022626

cytosolic ribosome

C

Seeded from EcoCyc 11.1[3].

required field missing

GO:0003735

structural constituent of ribosome

PMID:4587209[5]

IDA: Inferred from Direct Assay

F

Seeded from EcoCyc 11.1[3].

Data in Figure 1.

complete

GO:0005737

cytoplasm

C

Seeded from EcoCyc 11.1[3].

required fields missing

GO:0022625

cytosolic large ribosomal subunit

PMID:4587209[5]

IDA: Inferred from Direct Assay

C

Data in Figure 1.

complete

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Interactions


Partner TypePartnerNotesReferences

Protein

Subunits of 50S ribosomal subunit protein L7/L12 dimer

could be indirect

Protein

Subunits of 50S ribosomal protein complex L8

could be indirect

Protein

Subunits of 50S ribosomal subunit

could be indirect

Protein

Subunits of ribosome

could be indirect


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Notes

Localization

CompartmentDescriptionEvidenceNotes
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Notes

Structure and Physical Properties

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Physical Properties

Sequence

at EcoCyc

MSITKDQIIE AVAAMSVMDV VELISAMEEK FGVSAAAAVA VAAGPVEAAE EKTEFDVILK
AAGANKVAVI KAVRGATGLG LKEAKDLVES APAALKEGVS KDDAEALKKA LEEAGAEVEV K
Mol. Wt

12.3 kDa (calc) [2]

pI
Extinction coefficient

0 (calc based on 0 Y, 0 W, and 0 C residues)

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Domains/Motifs/Modification Sites

TypeResiduesDescriptionNotes

Modification Site

82

N6-methyllysine; partial

UniProt:P0A7K2

Modification Site

2 - 2

N-acetylserine; in L7

UniProt:P0A7K2

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Structure

Structures
  • Representative Escherichia coli structure:
    1RQT|A
    1-37 of 121 residues (E-value: 1.6e-13) (Percent Identity: 100.00)
  • Representative homolog:
    2FTC|E (Bos taurus)
    49-134 of 121 residues (E-value: 3.4e-09) (Percent Identity: 39.53)
  • View all other structures.
Models

View models at:

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Notes

Gene Product Resources

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Resource typeSourceNotes/Reference
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Notes

Accessions in Other Databases

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DatabaseAccessionNotes

EcoCyc (EcoliWiki Page)

EcoCyc:EG10873-MONOMER

UniProt (EcoliWiki Page)

UniProt:P0A7K2

PFAM (EcoliWiki Page)

PFAM:PF00542

RefSeq (EcoliWiki Page)

RefSeq:NP_418413

PDB (EcoliWiki Page)

PDB:1CTF


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Notes

Links

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NameURLComments
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References

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See Help:References for how to manage references in EcoliWiki.

  1. 1.0 1.1 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
  2. 2.0 2.1 2.2 2.3 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  3. 3.0 3.1 3.2 3.3 3.4 3.5 3.6 3.7 3.8 EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  4. 4.0 4.1 4.2 4.3 EcoCyc (release 12.5; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  5. 5.0 5.1 Wittmann-Liebold B (1973) Studies on the primary structure of 20 proteins from Escherichia coli ribosomes by means of an improved protein sequenator. FEBS Lett 36: 247-9 PubMed EcoliWiki page


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