rpsH:Gene Product(s) - EcoliWiki
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rpsH:Gene Product(s)

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Nomenclature Function Interactions Localization Sequence Domains Structure Resources Accessions Links References Suggestions

Nomenclature

Standard name

RpsH

Synonyms

30S ribosomal subunit protein S8[1], B3306[2][1], RpsH[2][1]

Product description

30S ribosomal subunit protein S8[2][3];

Component of ; 30S ribosomal subunit[2][3]; ribosome[2][3]

EC number (for enzymes)
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Notes

Function

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Gene Ontology
See Help:Gene_ontology for help entering or editing GO terms and GO annotations in EcoliWiki.

QualifierGO IDGO term nameReference(s)Evidence Codewith/fromAspectNotesStatus
GO:0030529

ribonucleoprotein complex

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0687

C

Seeded from EcoCyc 12.5 [4]

complete

GO:0019843

rRNA binding

GO_REF:0000004
GO_REF:0000020

IEA: Inferred from Electronic Annotation

SP_KW:KW-0699
HAMAP:MF_01302

F

Seeded from EcoCyc 12.5 [4]

complete

GO:0006417

regulation of translation

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0810

P

Seeded from EcoCyc 12.5 [4]

complete

GO:0006412

translation

GO_REF:0000002
GO_REF:0000020

IEA: Inferred from Electronic Annotation

InterPro:IPR000630
HAMAP:MF_01302

P

Seeded from EcoCyc 12.5 [4]

complete

GO:0005840

ribosome

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR000630

C

Seeded from EcoCyc 12.5 [4]

complete

GO:0003735

structural constituent of ribosome

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR000630

F

Seeded from EcoCyc 12.5 [4]

complete

GO:0003723

RNA binding

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0694

F

Seeded from EcoCyc 12.5 [4]

complete

GO:0045947

negative regulation of translational initiation

P

Seeded from EcoCyc 11.1[3].

required fields missing

GO:0006412

translation

PMID:4579428[5]

IDA: Inferred from Direct Assay

P

Seeded from EcoCyc 11.1[3].

Data shown in Table IV.

complete

GO:0030371

translation repressor activity

PMID:6445562[6]

IDA: Inferred from Direct Assay

F

Seeded from EcoCyc 11.1[3].

complete

GO:0005737

cytoplasm

C

Seeded from EcoCyc 11.1[3].

required fields missing

GO:0022627

cytosolic small ribosomal subunit

PMID:4587209[7]

IDA: Inferred from Direct Assay

C

complete

GO:0019843

rRNA binding

PMID:4912319[8]

IDA: Inferred from Direct Assay

F

complete

GO:0043488

regulation of mRNA stability

PMID:2643112[9]

IMP: Inferred from Mutant Phenotype

P

complete

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Interactions

Partner TypePartnerNotesReferences

Protein

Subunits of 30S ribosomal subunit

could be indirect

Protein

Subunits of ribosome

could be indirect


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Notes

Localization

CompartmentDescriptionEvidenceNotes
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Notes

Structure and Physical Properties

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Physical Properties

Sequence

at EcoCyc

MSMQDPIADM LTRIRNGQAA NKAAVTMPSS KLKVAIANVL KEEGFIEDFK VEGDTKPELE
LTLKYFQGKA VVESIQRVSR PGLRIYKRKD ELPKVMAGLG IAVVSTSKGV MTDRAARQAG
LGGEIICYVA
Mol. Wt

14.13 kDa (calc) [2]

pI
Extinction coefficient

4470 - 4595 (calc based on 3 Y, 0 W, and 1 C residues)

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Domains/Motifs/Modification Sites

TypeResiduesDescriptionNotes
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Structure

Structures
  • Representative Escherichia coli structure:
    2GY9|H
    1-127 of 130 residues (E-value: 2.2e-62) (Percent Identity: 100.00)
  • Representative homolog:
    1SEI|A (Geobacillus stearothermophilus)
    2-129 of 130 residues (E-value: 1.1e-30) (Percent Identity: 50.00)
  • View all other structures.
Models

View models at:

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Notes

Gene Product Resources

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Resource typeSourceNotes/Reference
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Notes

Accessions in Other Databases

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DatabaseAccessionNotes

EcoCyc (EcoliWiki Page)

EcoCyc:EG10907-MONOMER

UniProt (EcoliWiki Page)

UniProt:P0A7W7

PFAM (EcoliWiki Page)

PFAM:PF00410

RefSeq (EcoliWiki Page)

RefSeq:NP_417765

ModBase (EcoliWiki Page)

ModBase:P0A7W7

PDB (EcoliWiki Page)

PDB:1S03


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Notes

Links

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NameURLComments
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References

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See Help:References for how to manage references in EcoliWiki.

  1. 1.0 1.1 1.2 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
  2. 2.0 2.1 2.2 2.3 2.4 2.5 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  3. 3.0 3.1 3.2 3.3 3.4 3.5 3.6 EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  4. 4.0 4.1 4.2 4.3 4.4 4.5 4.6 EcoCyc (release 12.5; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  5. Held WA et al. (1973) Reconstitution of Escherichia coli 30 S ribosomal subunits from purified molecular components. J Biol Chem 248: 5720-30 PubMed EcoliWiki page
  6. Yates JL et al. (1980) In vitro expression of Escherichia coli ribosomal protein genes: autogenous inhibition of translation. Proc Natl Acad Sci U S A 77: 1837-41 PubMed EcoliWiki page
  7. Wittmann-Liebold B (1973) Studies on the primary structure of 20 proteins from Escherichia coli ribosomes by means of an improved protein sequenator. FEBS Lett 36: 247-9 PubMed EcoliWiki page
  8. Mizushima S & Nomura M (1970) Assembly mapping of 30S ribosomal proteins from E. coli. Nature 226: 1214 PubMed EcoliWiki page
  9. Mattheakis L et al. (1989) Retroregulation of the synthesis of ribosomal proteins L14 and L24 by feedback repressor S8 in Escherichia coli. Proc Natl Acad Sci U S A 86: 448-52 PubMed EcoliWiki page


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