rpsL:Gene Product(s) - EcoliWiki
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rpsL:Gene Product(s)

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Nomenclature Function Interactions Localization Sequence Domains Structure Resources Accessions Links References Suggestions

Nomenclature

Standard name

RpsL

Synonyms

30S ribosomal subunit protein S12[1], B3342[2][1], StrA[2][1], AsuB[2][1], RpsL[2][1]

Product description

30S ribosomal subunit protein S12[2][3];

Component of ; 30S ribosomal subunit[2][3]; ribosome[2][3]

EC number (for enzymes)
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Notes

Function

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Gene Ontology
See Help:Gene_ontology for help entering or editing GO terms and GO annotations in EcoliWiki.

QualifierGO IDGO term nameReference(s)Evidence Codewith/fromAspectNotesStatus
GO:0046677

response to antibiotic

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0046

P

Seeded from EcoCyc 12.5 [4]

complete

GO:0030529

ribonucleoprotein complex

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0687

C

Seeded from EcoCyc 12.5 [4]

complete

GO:0019843

rRNA binding

GO_REF:0000004
GO_REF:0000020

IEA: Inferred from Electronic Annotation

SP_KW:KW-0699
HAMAP:MF_00403

F

Seeded from EcoCyc 12.5 [4]

complete

GO:0015935

small ribosomal subunit

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR005679

C

Seeded from EcoCyc 12.5 [4]

complete

GO:0006412

translation

GO_REF:0000002
GO_REF:0000002
GO_REF:0000020

IEA: Inferred from Electronic Annotation

InterPro:IPR005679
InterPro:IPR006032
HAMAP:MF_00403

P

Seeded from EcoCyc 12.5 [4]

complete

GO:0005840

ribosome

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR006032

C

Seeded from EcoCyc 12.5 [4]

complete

GO:0003735

structural constituent of ribosome

GO_REF:0000002
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR005679
InterPro:IPR006032

F

Seeded from EcoCyc 12.5 [4]

complete

GO:0003723

RNA binding

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0694

F

Seeded from EcoCyc 12.5 [4]

complete

GO:0000049

tRNA binding

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0820

F

Seeded from EcoCyc 12.5 [4]

complete

GO:0022626

cytosolic ribosome

C

Seeded from EcoCyc 11.1[3].

required field missing

GO:0006412

translation

PMID:4579428[5]

IDA: Inferred from Direct Assay

P

Seeded from EcoCyc 11.1[3]. Data in Table IV.

complete

GO:0003735

structural constituent of ribosome

PMID:4587209[6]

IDA: Inferred from Direct Assay

F

Seeded from EcoCyc 11.1[3].

complete

GO:0005737

cytoplasm

C

Seeded from EcoCyc 11.1[3].

required fields missing

GO:0022627

cytosolic small ribosomal subunit

PMID:4587209[6]

IDA: Inferred from Direct Assay

C

complete

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Interactions

Partner TypePartnerNotesReferences

Protein

Subunits of 30S ribosomal subunit

could be indirect

Protein

Subunits of ribosome

could be indirect


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Notes

Localization

CompartmentDescriptionEvidenceNotes

cytoplasm

From EcoCyc[3]

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Notes

Structure and Physical Properties

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Physical Properties

Sequence

at EcoCyc

MATVNQLVRK PRARKVAKSN VPALEACPQK RGVCTRVYTT TPKKPNSALR KVCRVRLTNG
FEVTSYIGGE GHNLQEHSVI LIRGGRVKDL PGVRYHTVRG ALDCSGVKDR KQARSKYGVK RPKA
Mol. Wt

13.74 kDa (calc) [2]

pI
Extinction coefficient

5960 - 6460 (calc based on 4 Y, 0 W, and 4 C residues)

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Domains/Motifs/Modification Sites

TypeResiduesDescriptionNotes

Modification Site

89

3-methylthioaspartic acid

UniProt:P0A7S3

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Structure

Structures
  • Representative Escherichia coli structure:
    2GY9|L
    1-101 of 124 residues (E-value: 1.6e-52) (Percent Identity: 100.00)
  • Representative homolog:
    1FJG|L (Thermus thermophilus)
    4-126 of 124 residues (E-value: 2.0e-45) (Percent Identity: 72.36)
  • View all other structures.
Models

View models at:

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Notes

Gene Product Resources

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Resource typeSourceNotes/Reference
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Notes

Accessions in Other Databases

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DatabaseAccessionNotes

EcoCyc (EcoliWiki Page)

EcoCyc:EG10911-MONOMER

UniProt (EcoliWiki Page)

UniProt:P0A7S3

PFAM (EcoliWiki Page)

PFAM:PF00164

RefSeq (EcoliWiki Page)

RefSeq:NP_417801


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Notes

Links

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NameURLComments
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References

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See Help:References for how to manage references in EcoliWiki.

  1. 1.0 1.1 1.2 1.3 1.4 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
  2. 2.0 2.1 2.2 2.3 2.4 2.5 2.6 2.7 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  3. 3.0 3.1 3.2 3.3 3.4 3.5 3.6 3.7 EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  4. 4.0 4.1 4.2 4.3 4.4 4.5 4.6 4.7 4.8 EcoCyc (release 12.5; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  5. Held WA et al. (1973) Reconstitution of Escherichia coli 30 S ribosomal subunits from purified molecular components. J Biol Chem 248: 5720-30 PubMed EcoliWiki page
  6. 6.0 6.1 Wittmann-Liebold B (1973) Studies on the primary structure of 20 proteins from Escherichia coli ribosomes by means of an improved protein sequenator. FEBS Lett 36: 247-9 PubMed EcoliWiki page


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