rumA:Gene Product(s) - EcoliWiki
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rumA:Gene Product(s)

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Nomenclature Function Interactions Localization Sequence Domains Structure Resources Accessions Links References Suggestions

Nomenclature

Standard name

RumA

Synonyms

23S rRNA (uracil-5)-methyltransferase[1], B2785[2][1], YgcA[2][1], RumA[2][1]

Product description

23S ribosomal RNA 5-methyluridine methyltransferase[2][3]

EC number (for enzymes)
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Notes

Function

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Gene Ontology
See Help:Gene_ontology for help entering or editing GO terms and GO annotations in EcoliWiki.

QualifierGO IDGO term nameReference(s)Evidence Codewith/fromAspectNotesStatus
GO:0051539

4 iron, 4 sulfur cluster binding

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0004

F

Seeded from EcoCyc 12.5 [4]

complete

GO:0051536

iron-sulfur cluster binding

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0411

F

Seeded from EcoCyc 12.5 [4]

complete

GO:0046872

metal ion binding

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0479

F

Seeded from EcoCyc 12.5 [4]

complete

GO:0016740

transferase activity

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0808

F

Seeded from EcoCyc 12.5 [4]

complete

GO:0008757

S-adenosylmethionine-dependent methyltransferase activity

GO_REF:0000020

IEA: Inferred from Electronic Annotation

HAMAP:MF_01010

F

Seeded from EcoCyc 12.5 [4]

complete

GO:0008173

RNA methyltransferase activity

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR001566

F

Seeded from EcoCyc 12.5 [4]

complete

GO:0008168

methyltransferase activity

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0489

F

Seeded from EcoCyc 12.5 [4]

complete

GO:0006396

RNA processing

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR001566

P

Seeded from EcoCyc 12.5 [4]

complete

GO:0006364

rRNA processing

GO_REF:0000004
GO_REF:0000020

IEA: Inferred from Electronic Annotation

SP_KW:KW-0698
HAMAP:MF_01010

P

Seeded from EcoCyc 12.5 [4]

complete

GO:0005506

iron ion binding

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0408

F

Seeded from EcoCyc 12.5 [4]

complete

GO:0003723

RNA binding

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR001566

F

Seeded from EcoCyc 12.5 [4]

complete

GO:0005737

cytoplasm

C

Seeded from Riley et al 2006 [1].

required fields missing

GO:0009451

RNA modification

P

Seeded from EcoCyc 11.1[3].

required fields missing

GO:0016072

rRNA metabolic process

P

Seeded from EcoCyc 11.1[3].

required fields missing

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Interactions

Partner TypePartnerNotesReferences
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Notes

Localization

CompartmentDescriptionEvidenceNotes
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Notes

Structure and Physical Properties

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Physical Properties

Sequence

at EcoCyc

MAQFYSAKRR TTTRQIITVS VNDLDSFGQG VARHNGKTLF IPGLLPQENA EVTVTEDKKQ
YARAKVVRRL SDSPERETPR CPHFGVCGGC QQQHASVDLQ QRSKSAALAR LMKHDVSEVI
ADVPWGYRRR ARLSLNYLPK TQQLQMGFRK AGSSDIVDVK QCPILAPQLE ALLPKVRACL
GSLQAMRHLG HVELVQATSG TLMILRHTAP LSSADREKLE RFSHSEGLDL YLAPDSEILE
TVSGEMPWYD SNGLRLTFSP RDFIQVNAGV NQKMVARALE WLDVQPEDRV LDLFCGMGNF
TLPLATQAAS VVGVEGVPAL VEKGQQNARL NGLQNVTFYH ENLEEDVTKQ PWAKNGFDKV
LLDPARAGAA GVMQQIIKLE PIRIVYVSCN PATLARDSEA LLKAGYTIAR LAMLDMFPHT
GHLESMVLFS RVK
Mol. Wt

48.05 kDa (calc) [2]

pI
Extinction coefficient

35410 - 36285 (calc based on 9 Y, 4 W, and 7 C residues)

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Domains/Motifs/Modification Sites

TypeResiduesDescriptionNotes

Domain

10 - 68

TRAM

UniProt:P55135

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Structure

Structures
  • Representative Escherichia coli structure:
    2BH2|A
    1-433 of 433 residues (E-value: 2.1e-231) (Percent Identity: 100.00)
  • Representative homolog:
    2JJQ|A (Pyrococcus abyssi)
    267-419 of 433 residues (E-value: 1.0e-27) (Percent Identity: 32.53)
  • View all other structures.
Models

View models at:

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Notes

Gene Product Resources

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Resource typeSourceNotes/Reference
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Notes

Accessions in Other Databases

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DatabaseAccessionNotes

EcoCyc (EcoliWiki Page)

EcoCyc:EG11247-MONOMER

UniProt (EcoliWiki Page)

UniProt:P55135

PFAM (EcoliWiki Page)

PFAM:PF01938

RefSeq (EcoliWiki Page)

RefSeq:NP_417265

ModBase (EcoliWiki Page)

ModBase:P55135

PDB (EcoliWiki Page)

PDB:1UWV


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Notes

Links

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NameURLComments
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References

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See Help:References for how to manage references in EcoliWiki.

  1. 1.0 1.1 1.2 1.3 1.4 1.5 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
  2. 2.0 2.1 2.2 2.3 2.4 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  3. 3.0 3.1 3.2 EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  4. 4.00 4.01 4.02 4.03 4.04 4.05 4.06 4.07 4.08 4.09 4.10 EcoCyc (release 12.5; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7


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