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References Suggestions

Standard Name


Gene Synonym(s)

ECK3599, b3609, JW3584[1], JW3584

Product Desc.


Component of Sec Protein Secretion Complex[2][3]

Protein export chaperone; SecB helps SecA deliver proteins to the SecYE core translocon; general protein chaperone[4]

Product Synonyms(s)

protein export chaperone[1], B3609[2][1], SecB[2][1] , ECK3599, JW3584, b3609

Function from GO

Molecular Function

Biological Process

Knock-Out Phenotype

non lethal. SecB null strains are deficient in post translational targeting of some secretion and outer membrane proteins.[5]


transcription unit(s): gpsA[2]

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Penultimate Ser residue missing from purified protein could be a proteolytic artifact.[4]


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  1. 1.0 1.1 1.2 1.3 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
  2. 2.0 2.1 2.2 2.3 2.4 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  3. 3.0 3.1 EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  4. 4.0 4.1 EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.
  5. Kumamoto, CA & Beckwith, J (1985) Evidence for specificity at an early step in protein export in Escherichia coli. J. Bacteriol. 163 267-74 PubMed EcoliWiki page