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tufA:Quickview

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Standard Name

tufA

Gene Synonym(s)

ECK3326, b3339, JW3301, kirT, pulT, G7976[1][2]

Product Desc.

elongation factor Tu[2][3]

EF-Tu, Elongation Factor-Translation, unstable; GTP-dependent binding of aa-tRNA to the A-site of ribosomes; has intrinsic GTPase activity when bound to kirromycin[4]

Product Synonyms(s)

protein chain elongation factor EF-Tu (duplicate of tufB)[1], protein chain elongation factor EF-Tu (duplicate of tufA)[1], B3339[2][1], PulT[2][1], KirT[2][1], TufA[2][1], EF-Tu[2][1] , ECK3326, JW3301, kirT, pulT, b3339

Function from GO
Knock-Out Phenotype
Regulation/Expression

transcription unit(s): fusA-tufA[2], rpsLG-fusA-tufA[2]

Regulation/Activity
Quick Links

porteco.png EcoCyc.gif regulondb.jpg

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Notes

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tufA and tufB both encode EF-Tu

tufA encodes an essential function, with duplicate gene tufB, such that tufA or tufB can be deleted, but the double mutant is inviable. HT_Cmplx23_Cyt: FusA+Tsf+TufA.HT_Cmplx4_Cyt: Tsf+TufA.[4]



References

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  1. 1.0 1.1 1.2 1.3 1.4 1.5 1.6 1.7 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
  2. 2.0 2.1 2.2 2.3 2.4 2.5 2.6 2.7 2.8 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  3. EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  4. 4.0 4.1 EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.