|Quickview||Gene||Gene Product(s)||Expression||Evolution||On One Page|
ECK4238, b4243, JW5755, JW5755, yjgF
Function unknown; Salmonella ortholog required for full IlvE activity and for the dependence of the alternative pyrimidine biosynthesis (APB) pathway of thiamine biosynthesis upon the oxidative pentose phosphate pathway; serine sensitivity; trimeric
|Function from GO||
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YjgF, RutC, TdcF, YoaB and YjgH are paralogs and members of a highly conserved YjgF family (pfam:PF01042) with diverse mutant phenotypes and unknown molecular function; the family members form homotrimers, some binding 2-ketoglutarate or related compounds. The rat homolog PSP (perchloric acid-soluble protein) has been reported to have endoribonuclease activity, Endoribonuclease L, against ss mRNA, inhibiting translation, but this activity has not been demonstrated for other members.
- Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
- EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
- EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
- EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.